T.C. Stevens, C. Cywes-Bentley, D. Putnam, Y-F Chang, B.D. Jones, G.B. Pier, M.P DeLisa.  Immunization with outer membrane vesicles displaying a conserved surface polysaccharide antigen generates broadly anti-microbial antibodies. Proc. Nat’l Acad Sci USA (2018) (in press).

S.Y. Wong and D. Putnam. The stochastic effect of polydispersity on polymeric DNA delivery vectors. J. App Poly Sci (2017) (in press)

H.C. Watkins, C.L. Pagan, H.R. Childs, S. Posada, A. Chau, J. Rios, C. Guarino, M.P. DeLisa, G.R. Whittaker, D. Putnam. A Single Dose and Long Lasting Vaccine against Pandemic Influenza through the Controlled Release of a Heterospecies Tandem M2 Sequence Embedded within Detoxified Bacterial Outer Membrane Vesicles Vaccine (2017) 35:5373-5380

OE Kaymakcalan, J Jin, Z Sun, MC McCorry, NG Ricapito, KA Morrison, D Putnam, J.A. Spector.  Transient Phase Behavior of an Elastomeric Biomaterial Applied to Abdominal Laparotomy Closure. Acta Biomaterialia (2017) in press

RA Eguiluz, SG Cook, MC Tan, CN Brown, NJ Pacifici, MS Samak, LJ Bonassar, D Putnam, D Gourdon. Synergistic interactions of a synthetic lubricin mimetic with fibronectin for enhanced wear protection. Frontiers in Bioengineering and Biotechnology (2017) (in press).

S. Yazdi, DJ Chen, D Putnam. Microparticles with Variable Architectures from a Series of Symmetrical Lipids Based on Metabolic Synthons (in revision).

J.C. Kohn, F. Bordeleau, J. Miller, H.C. Watkins, S. Modi, J. Ma, J. Azar, D. Putnam, C.A. Reinhart-King. Beneficial effects of exercise on arterial stiffness are short-lived (2017) in press.

Y.M.D. Gnopo, H.C. Watkins, T.C. Stevenson, M.P. DeLisa, D. Putnam.  Designer outer membrane vesicles as immunomodulatory systems – reprogramming bacteria for vaccine delivery. Advanced Drug Delivery Reviews (invited) (2017) in press

K.J. Samaroo, M.Tan, R.C. Andresen Eguiluz, D. Gourdon, D. Putnam, L.J. Bonassar.  Tunable lubricin-mimetics for boundary lubrication of cartilage. Biotribology (2017) 9:18-23, 2017.

HC Watkins, CG Rappazzo, JS Higgins, X Sun, N Brock, A Chau, A Misra, JPB Cannizzo, MR King, TR Maines, CA Leifer, GR Whittaker, MP DeLisa, D Putnam. Safe recombinant outer membrane vesicles that display M2e elicit heterologous influenza protection (2017) Molecular Therapy 25(4):989-1002

JL Valentine, L Chen, EC Perregaux, KB Weyant, JA Rosenthal, C Heiss, P Azadi, AC Fisher, D Putnam D, GR Moe, JH Merritt, MP DeLisa. Immunization with Outer Membrane Vesicles Displaying Designer Glycotopes Yields Class-Switched, Glycan-Specific Antibodies (2016) Cell Chem Biol. 23(6):655-65

B.M.Cooper and D. Putnam.  Polymers for siRNA delivery: A Critical Assessment of Current Technology Prospects for Clinical Application.  ACS Biomaterials Science & Engineering (2016)

K.J. Samaroo, M. Tan, D. Putnam, L.J. Bonassar.  Binding and Lubricating Properties of Biomimetic Boundary Lubricants for Articular Cartilage.  Journal of Orthopaedic Research (2017) 35(3): 548–557, DOI: 10.1002/jor.23370

N.G. Ricapito, J. Mares, D. Petralia, D. Putnam. Insight into the Unexpectedly Rapid Degradation of Dihydroxyacetone-Based Hydrogels.  Macromolecular Chemistry and Physics (2016) 217:1917-1925.  DOI: 10.1002/macp.201600170.

Linxiao Chen , Jenny L Valentine , Chung-Jr Huang , Christine E Endicott , Tyler D Moeller , Jed A Rasmussen , Joshua R Fletcher , Joseph M Boll , Joseph A Rosenthal , Justyna Dobruchowska , Zhirui Wang , Christian Heiss , Parastoo Azadi , David Putnam , M. Stephen Trent , Bradley D Jones , Matthew P DeLisa. Outer membrane vesicles displaying engineered glycotopes elicit protective antibodies. Proc. Nat’l Acad Sci (2016) in press.

C. Garrett Rappazzo, Hannah C. Watkins, Cassandra M Guarino, Annie Chau, Jody L. Lopez, Matthew P DeLisa, Cynthia A. Leifer, Gary R Whittaker, David Putnam.  Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/c mice.

N.G. Ricapito, C. Ghobril, H. Zhang, M.W. Grinstaff, D. Putnam.  Synthetic Biomaterials from Metabolically Derived Synthons.  Chemical Reviews (2016) 116, 2664-2704.

J.L. Rios, G. Lu, N.E. Seo, T. Lambert, D. Putnam.  Prolonged Release of Bioactive Model Proteins from Anionic Microgels Fabricated with a New Microemulsion Approach. Pharm Res (2015) .

L. Crawford, J. Rosch, D. Putnam. Concepts, Technologies, and Practices for Drug Delivery Past the Blood-Brain Barrier to the Central Nervous System.  J. Controlled Release (2016) 240:251-266.

L. Chen, J.L. Baker, C-Jr Huang, C.E. Endicott, J.A. Rasmussen, J.R. Fletcher, C. Heiss, P.Azadi, D. Putnam, B.D. Jones, M.P. DeLisa. Glycoengineered outer membrane vesicles displaying O-antigen polysaccharides elicit protective antibodies against type A Francisella tularensis (2014) in review

L. Crawford, J. Higgins, D. Putnam. A Simple and Sensitive Method to Quantify Biodegradable Nanoparticle Biodistribution using Europium Chelates. Sci. Reports 5, 13177, doi: 10.1038/srep13177 (2015)

J.A. Rosenthal, C-Jr. Huang, A.M. Doody, T. Leung, K. Mineta, D.D. Feng, E.C. Wayne, N. Nishimura, C. Leifer, M.P. DeLisa, S. Mendez, D. Putnam. Mechanistic Insight into the TH1-biased Immune Response to Recombinant Subunit Vaccines Delivered by Probiotic Bacteria-Derived Outer Membrane Vesicles. PLoS One (2014) 10.1371/journal.pone.0112802.

L. Crawford, D. Putnam. Synthesis and Characterization of Macromolecular Rhodamine Tethers and Their Interactions with P-glycoprotein. Bioconjugate Chemistry (2014) 25:1462–1469.

J.L. Baker, L. Chen, J.A. Rosenthal, D. Putnam, M.P. DeLisa,. Microbial biosynthesis of designer outer membrane vesicles (2014) Curr Opin Biotechnol. 29C:76-84.

J.N. Korley, S. Yazdi, D. Putnam. One-step Synthesis of Polyesters from Metabolic Synthons (2014) (in review)

D. Putnam Design and development of effective siRNA delivery vehicles. (2014). Proc Nat’l Acad Sci USA 111:3903-3904

J.A. Rosenthal, J.L. Baker, L. Chen, D. Putnam, M.P. DeLisa. Pathogen-like particles: biomimetic vaccine carriers engineered at the nanoscale. (2013) Curr Opin Biotechnol 28:51–58.

J.A. Rosenthal, T. Leung, D. Putnam. Low-dose Recombinant Vaccine Antigen Delivery By Engineered Outer Membrane Vesicles. (2013) Nano LIFE 3 (3) (doi: 10.1142/S1793984413420026).

J.R. Weiser, A. Yueh, D. Putnam. Protein Release From Dihydroxyacetone Based Poly(carbonate-ester) Matrices (2013) Acta Biomaterialia 9:8245-8253.

J.M. Pelet and D. Putnam. Poly(acrylic acid) Undergoes Partial Esterification During RAFT Synthesis in Methanol and Interchain Disulfide Bridging Upon
NaOH Treatment. (2012) Macromol. Chem. Phys. 213:2536–2540.

J.M. Pelet and D. Putnam. A Combinatorial Library of Bi-functional Polymeric Vectors for siRNA Delivery In Vitro. Pharm. Res. (2013) 30:362-76.

J.R. Weiser, N.G. Ricapito, A. Yueh, E.L. Weiser, D. Putnam. A mechanistic analysis of the quantitation of α-hydroxy ketones by the bicinchoninic acid assay. Analytical Biochemistry (2012) 430:116-122.

W.R. Reisacher, D. Liotta, S. Yazdi, D. Putnam. Desensitizing Mice to Ovalbumin through Subcutaneous Microsphere Immunotherapy (SMITH) Allergy & Rhinology (2011) 1:390-395.

J. Weiser, P.N. Zawaneh, D. Putnam. Poly(carbonate-ester)s of Dihydroxyacetone and Lactic Acid as Potential Biomaterials. Biomacromolecules (2011) 12:977-986.

J.M. Pelet and D. Putnam. An In-Depth Analysis of Polymer-Analogous Conjugation using DMTMM. Bioconj. Chem. (2011) 22:329-337.

P.N. Zawaneh,S.P. Singh,R.F. Padera, P.W. Henderson, J.A. Spector, D. Putnam. Design of an injectable synthetic and biodegradable surgical biomaterial. Proc. Nat’l Acad Sci USA (2010) 107:11014-11019.

D.J. Chen, N, Osterrider, S.M. Metzgerb, E. Buckles, A.M. Doody, M.P DeLisa, D. Putnam. Delivery of Foreign Antigens by Engineered Outer Membrane Vesicle Vaccines. Proc. Nat’l Acad. Sci. USA (2010) 107:3099-3104.

P.W. Henderson, D.J.M. Kadouch, S.P. Singh, P.N. Zawaneh, J. Weiser, S. Yazdi, A. Weinstein, U. Krotscheck, D. Putnam. J. Spector. A Rapidly Resorbable Hemostatic Biomaterial Based on Dihydroxyacetone. J. Biomed. Mater. Res. Pt A. (2010) 93:776-782.

J.M. Pelet and D. Putnam. High molecular weight poly(methacrylic acid) with narrow polydispersity by RAFT polymerization. Macromolecules (2009) 42:1494–1499.

S.Y. Wong, N. Sood, D. Putnam. Combinatorial evaluation of cations, pH-sensitive and hydrophobic moieties for polymeric vector design Molecular Therapy (2009) 17:480-490.

S.Y. Wong, T. Chan, D. Putnam. Simple and Economical High-Throughput Equilibrium Dialysis System. J. Combinatorial Chemistry (2009) 11:202–205.

D. Putnam. The heart of the matter. Nature Materials (2008) 7:836-837.

P.N. Zawaneh and D. Putnam. Materials in Surgery: A Review of Biomaterials in Post Surgical Tissue Adhesion and Seroma Prevention. Tissue Engineering Part B, Reviews (2008) 14:1-15.

J-Y Kim, A.M. Doody, D.J. Chen, G.H. Cremona, D. Putnam and M.P. DeLisa. Engineered bacterial outer membrane vesicles with enhanced functionality.
Journal of Molecular Biology (2008) 380:51-66.

S.Y. Wong, J. Pelet and D. Putnam. Polymer systems for gene delivery – Past, present, and future. Progress in Polymer Science (invited) (2007) 32:799-837.

S.Y. Wong and D. Putnam. Overcoming limiting side reactions associated with an NHS-activated precursor of poly(methacrylamide)-based polymers. Bioconjugate Chemistry (2007) 18:970-982.

P.N. Zawaneh, A.M. Doody, A.N. Zelikin, D. Putnam. Diblock Copolymers Based on Dihydroxyacetone and Ethylene Glycol: Synthesis, Characterization and Nanoparticle Formulation. Biomacromolecules (2006) 7:3245-3251.

A.N. Zelikin, P.N. Zawaneh, D. Putnam. A Functionalizable Biomaterial based on Dihydroxyacetone, an Intermediate of Glucose Metabolism. Biomacromolecules (2006) 7:3239-3244.

A.M. Doody, J.N. Korley, K.P. Dang, P.N. Zawaneh, D. Putnam. Characterizing the structure/function parameter space of hydrocarbon-conjugated branched polyethylenimine for DNA delivery in vitro J. Controlled Release (2006) 116:227-237.

A.C.R.Grayson, J. Ma, D. Putnam. Kinetic Efficacy Analysis of RNA Interference in Stably and Transiently Expressing Cell Lines. Molecular Pharmaceutics (2006) 23:1868-1876.

A.C.R Grayson, A.M. Doody, D. Putnam. Biophysical and Structural Characterization of Polyethylenimine-Mediated siRNA Delivery in Vitro. Pharmaceutical Research (2006) 23:1868-1876.

D. Putnam. Polymers for Gene Delivery across Length Scales. Nature Materials (invited) (2006) 5:439-451.

A. Doody and D. Putnam. RNA-interference Effectors and their Delivery. Critical Reviews in Therapeutic Drug Carrier Systems (invited), (2006) 23:137-164.

A Doody and D Putnam. Identification of compartments involved in mammalian subcellular trafficking pathways by indirect immunofluorescence. Methods in Molecular Medicine (2006) 127:127-136.

A. Zelikin and D. Putnam. Poly(carbonate-acetal)s from the Dimer of Dihydroxyacetone Macromolecules (2005) 38:5532-5537.

D.J. Chen, B.S. Majors, A. Zelikin, D. Putnam. Structure-function relationships of gene delivery vectors in a limited polycation library. Journal of Controlled Release (2005) 103:273-283.

D.G. Anderson, D. Putnam, E.R. Lavik, T. Mahmood, R. Langer. Biomaterial microarrays: rapid, microscale screening of polymer-cell interaction. Biomaterials (2005) 26:4892-4897.

C. Wang, G. Qing, D. Ting, D. Ngyuen, H-R. Shen, J. Chen, H. Eisen, J. Heller, R. Langer, D. Putnam Molecularly engineered poly(orthoester) microspheres for enhanced delivery of DNA vaccines Nature Materials (2004) 3:190-196.

S-W Wang, J. Monagle, C. McNulty, D. Putnam, H. Chen. Determination of P-glycoprotein inhibition by excipients and their combinations using an integrated high-throughput process. Journal of Pharmaceutical Sciences (2004) 93:2755-2767.

A. Zelikin, E. Trukhanova, D. Putnam, V. Izumrudov, A. Litmanovich. Competitive reactions in solutions of poly-L-histidine, calf thymus DNA and synthetic polyanions. Determining the binding constants of polyelectrolytes. Journal of the American Chemical Society (2003) 125:13693-13699.

D. Putnam, A.N. Zelikin, V.A. Izumrudov, and R. Langer. Polyhistidine-PEG:DNA Nanocomposites for Gene Delivery, Biomaterials (2003) 24:4425-4433.

C. Locher, D. Putnam, R. Langer, S. Witt, B. Ashlock, J. Levy. Enhancement of HIV env DNA vaccine using a novel polycationic nanoparticle formulation. Immunol. Letters (2003) 90:67-70.

D.M. Lynn, D.G. Anderson, D. Putnam and R. Langer. Accelerated Discovery of Synthetic Transfection Vectors: Parallel Synthesis and Screening of a Degradable Polymer Library. Journal of the American Chemical Society (2001) 123:8155-8156.

A.N. Zelikin, D. Putnam, P. Shastri, R. Langer, V.A. Izumrodov. Aliphatic Ionenes as Gene Delivery Agents: Elucidation of Structure-function Relationships Through Modification of Charge Density and Polymer Length. Bioconjugate Chemistry (2002) 13:548-553.

C. Perez, A. Sanchez, D. Putnam, D. Ting, R. Langer, M.J. Alonso. Poly(lactic acid)-poly(ethylene glycol) Nanoparticles as New Carriers for the Delivery of Plasmid DNA Journal of Controlled Release (2001) 75:211-224.

D. Putnam, C. Gentry, D. Pack, and R. Langer. Polymer-based Gene Delivery with Low Cytotoxicity by a Unique Balance of Side-chain Termini Proceedings of the National Academy of Sciences, USA (2001) 98:1200-1205.

D. Pack, D. Putnam, and R. Langer. Design of Imidazole-Containing Endosomolytic Biopolymers for Gene Delivery. Biotechnology and Bioengineering (2000) 67:217-223.

D. Putnam and R. Langer. Poly(4-hydroxy-L-proline ester): Low-temperature Polycondensation and Plasmid DNA Complexation. Macromolecules (1999) 32:3658-3662.

S. Ando, D. Putnam, D. Pack, and R. Langer. Preparation of High Supercoiled DNA Content Microspheres via Cryopreparation and Carbohydrate Stabilization. Journal of Pharmaceutical Sciences (1999) 88:126-130.

D. Putnam, J.-G. Shiah, and J. Kopecek. Intracellularly Biorecognizable Derivatives of 5-Fluorouracil: Implications for Targeted Delivery in the Human Condition. Biochemical Pharmacology (1996) 52:957-962.

D. Putnam. Antisense Strategies and Therapeutic Applications. American Journal of Health-System Pharmacy (1996) 53:151-160.

D. Putnam and J. Kopecek. Enantioselective Release of 5-Fluorouracil from N-(2-Hydroxypropyl)methacrylamide-Based Copolymers via Lysosomal Enzymes. Bioconjugate Chemistry (1995) 6:483-492.

D. Putnam and J. Kopecek . Polymer Conjugates with Anticancer Activity. Advances in Polymer Science (1995) 122:55-123.

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